Preview Extract
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Date:
Chapter 2 – Preconception Nutrition
True / False
1. The subfertility of one partner can be compensated by the reproductive capacity of the other partner.
a. True
b. False
ANSWER: True
2. Weight gain is the recommended first-line treatment for amenorrhea related to low body weight.
a. True
b. False
ANSWER: True
3. During the preconception period, factors such as weight status; folic acid, iron, and antioxidant intake; and dietary
supplement use would be addressed as part of the nutrition care process.
a. True
b. False
ANSWER: True
4. Obese women tend to have higher levels of estrogen, androgens, and leptin than nonobese women.
a. True
b. False
ANSWER: True
5. The hypothalamus is responsible for temperature regulation and sleep.
a. True
b. False
ANSWER: True
6. Prostate gland is an endocrine gland that contributes fluid to the semen.
a. True
b. False
ANSWER: False
7. It is easier and more efficient to build up iron stores before pregnancy than during pregnancy.
a. True
b. False
ANSWER: True
8. Nutrient requirements for both men and women should be met through dietary supplements rather than foods.
a. True
b. False
ANSWER: False
9. Fertility usually resumes immediately after discontinuing the use of contraceptives.
a. True
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Chapter 2 – Preconception Nutrition
b. False
ANSWER: False
10. In Indonesia, a couple applying for a marriage license have to receive advice on iron status from those dispensing the
license.
a. True
b. False
ANSWER: True
11. The desire of couples planning for pregnancy to have a healthy newborn makes the preconceptional period too
stressful to address any psychosocial needs.
a. True
b. False
ANSWER: False
Multiple Choice
12. Fertility refers to the _____.
a. biological capacity to bear children
b. desire to bear children
c. actual production of children
d. number of births per 1000 miscarriages
e. number of births per 1000 women of childbearing age
ANSWER: c
13. Infertility is generally defined as the lack of conception after _____ of unprotected intercourse.
a. 3 months
b. 6 months
c. 9 months
d. 1 year
e. 1.5 year
ANSWER: d
14. Which of the following factors is related to altered fertility in women?
a. Anorexia nervosa
b. Inadequate zinc status
c. Exposure to lead
d. High intake of soy foods
e. Halogen exposure
ANSWER: a
15. The protein secreted by fat cells that, by binding to specific receptor sites in the hypothalamus, decreases appetite,
increases energy expenditure, and stimulates gonadotropin secretion is called _____.
a. estrogen
b. progesterone
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c. collagen
d. leptin
e. testosterone
ANSWER: d
16. The most common known cause of miscarriage for women is _____.
a. a structural abnormality in the uterus
b. the presence of a severe defect in the fetus
c. maternal infection
d. an endocrine disorder
e. physical trauma to the mother
ANSWER: b
17. The _____ phase of the menstrual cycle occurs after ovulation.
a. follicular
b. luteal
c. estrogen
d. primordial
e. menstruation
ANSWER: b
18. The first half of the menstrual cycle is called the _____ phase.
a. follicular
b. luteal
c. estrogen
d. primordial
e. menses
ANSWER: a
19. Ovulation results from a surge in the _____ hormone.
a. estrogen
b. progesterone
c. luteinizing
d. follicle-stimulating
e. gonadotropin-releasing
ANSWER: c
20. The two hormones secreted by the pituitary gland during the follicular phase of menstrual cycle are _____.
a. follicle-stimulating hormone and progesterone
b. progesterone and estrogen
c. follicle-stimulating hormone and luteinizing hormone
d. luteinizing hormone and progesterone
e. luteinizing hormone and estrogen
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Chapter 2 – Preconception Nutrition
ANSWER: c
21. The _____ releases _____, stimulating the pituitary gland to release FSH and LH.
a. ovary; estrogen
b. ovary; progesterone
c. uterus; progesterone
d. hypothalamus; estrogen
e. hypothalamus; gonadotropin-releasing hormone
ANSWER: e
22. After ovulation, the corpus luteum secretes _____, which _____.
a. progesterone and estrogen; stimulate the ovulation of a second egg
b. progesterone and estrogen; stimulate development of the endometrium
c. follicle-stimulating hormone and luteinizing hormone; stimulate development of the endometrium
d. luteinizing hormone and estrogen; facilitate fertilization of the egg
e. luteinizing hormone and estrogen; stimulate ovulation of a second egg
ANSWER: b
23. A menstrual flow results from _____.
a. the implantation of a fertilized ovum in the endometrium
b. a decrease in progesterone and estrogen levels
c. the release of gonadotropin-releasing hormone by the hypothalamus
d. the production of prostaglandins by the uterus
e. the release of progesterone and estrogen by the corpus luteum
ANSWER: b
24. In a typical 28-day cycle, when would levels of luteinizing hormone most likely be the highest?
a. day 1
b. day 7
c. day 10
d. day 14
e. day 28
ANSWER: d
25. Cramps and other side effects of menstruation can be traced to the production of _____ by the uterus.
a. progesterone
b. estrogen
c. prostaglandins
d. luteinizing hormone
e. gonadotropin-releasing hormone
ANSWER: c
26. Obesity is generally indicated by body mass index values over _____ kg/m2.
a. 20
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Chapter 2 – Preconception Nutrition
b. 29
c. 25.5
d. 40
e. 30
ANSWER: e
27. In males, mature sperm are stored in the _____.
a. testes
b. vas deferens
c. prostate gland
d. seminal vesicles
e. epididymis
ANSWER: e
28. Which hormone(s) trigger(s) the production of testosterone by the testes?
a. follicle-stimulating hormone
b. luteinizing hormone
c. progesterone
d. luteinizing hormone and progesterone
e. follicle-stimulating hormone and luteinizing hormone
ANSWER: e
29. Exposure to high levels of _____ is related to decreased sperm production and abnormal sperm motility and shape.
a. zinc
b. iron
c. lead
d. iodine
e. selenium
ANSWER: c
30. Endometriosis is defined as _____.
a. scarring and blockage of the fallopian tubes
b. the condition in which endometrial tissue becomes embedded within other body tissues
c. a modification of pregnancy hormones that results in infertility
d. an infection of the cervix
e. the inability to get pregnant
ANSWER: b
31. The leading diagnoses related to infertility are _____.
a. endocrine abnormalities that modify hormonal regulation of fertility
b. unknown causes
c. environmental contaminants such as lead and mercury
d. overweight and obesity in men
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Chapter 2 – Preconception Nutrition
e. sexually transmitted diseases
ANSWER: a
32. Which factor would be more likely to affect female fertility than male fertility?
a. inadequate body fat
b. poor iron stores
c. high alcohol intake
d. excessive body fat
e. excessive exercise
ANSWER: b
33. Which factor has been linked to impaired fertility in males but not females?
a. high sperm count
b. oxidative stress
c. exercise
d. excessive heat to the gonads
e. Poor iron stores
ANSWER: d
34. Which statement related to male and female fertility is true?
a. During a female’s fertile years, approximately 1000 ova will mature and be released for possible fertilization.
b. For males, sperm numbers and viability decrease somewhat after age 30.
c. For both males and females, the quality of eggs and sperm decrease somewhat with age.
d. Females are born with mature eggs.
e. Males produce sperm from birth until death.
ANSWER: c
35. Pelvic inflammatory disease (PID) can _____.
a. cause less estrogen to be secreted, thus blocking ovulation
b. lead to scarring and blockage of the fallopian tubes
c. cause sperm to become less viable in males
d. increase the lining of the endometrium
e. decrease zinc absorption
ANSWER: b
36. A body mass index (BMI) greater than _____ kg/m2 is typically needed to sustain normal reproductive function in
women.
a. 17
b. 20
c. 25
d. 30
e. 35
ANSWER: b
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Chapter 2 – Preconception Nutrition
37. An anovulatory cycle is _____.
a. the absence of a menstrual cycle
b. a menstrual cycle in which ovulation does not occur
c. an abnormally short menstrual cycle
d. an abnormally long menstrual cycle
e. a menstrual cycle in which more than one egg is ovulated
ANSWER: b
38. Which dietary component can protect cells of the reproductive system from damage by free radicals?
a. sodium
b. calcium
c. iron
d. iodine
e. antioxidants
ANSWER: e
39. Which of the following can be defined as an alteration in the normal sequence of a gene?
a. allele
b. gene variant
c. functional hypothalamic amenorrhea
d. gene splicing
e. endometriosis
ANSWER: b
40. Folic acid is a synthetic form of which vitamin?
a. A
b. C
c. B
d. E
e. D
ANSWER: c
41. _____ is a pea-sized gland located at the base of the brain.
a. Hypothalamus
b. Pituitary gland
c. Clitoris
d. Testes
e. Epididymis
ANSWER: b
42. The development of facial and heart abnormalities in the fetus has been linked to _____ by the mother.
a. excessive vitamin A intake
b. decreased intake of iodine
c. excessive protein intake
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Chapter 2 – Preconception Nutrition
d. increased energy expenditure
e. a decreased folate intake
ANSWER: a
43. DNA methylation _____.
a. modifies gene function in the fetus during late pregnancy
b. activates gene expression
c. is an abnormal part of development
d. is needed for cellular differentiation
e. is unaffected by nutritional intake
ANSWER: d
44. Spina bifida is an example of a _____.
a. neural tube defect
b. DNA modification
c. gene variant
d. nutritional deficiency
e. metabolic programming mechanism
ANSWER: a
45. The risk of early delivery is increased by _____.
a. excessive vitamin A intake
b. iron deficiency
c. iodine deficiency
d. high levels of lead in the maternal blood
e. diabetes
ANSWER: b
46. Refined grain products are often fortified with _____ to decrease rates of _____.
a. folic acid; neural tube defects
b. iron; neural tube defects
c. iodine; late delivery
d. folic acid; late delivery
e. vitamin B; fetal heart abnormalities
ANSWER: a
47. What nutritional and health advice would a doctor likely give to a preconceptional woman?
a. The woman’s physical activity should be limited to less than 30 minutes per day.
b. The woman should eat mostly dark green vegetables.
c. At least half of the woman’s grain intake should be from refined grains.
d. The woman’s vitamin intake should be at least 10,000 IU of vitamin A per day.
e. The woman should consume 400 mcg of folic acid in addition to dietary folate.
ANSWER: e
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Chapter 2 – Preconception Nutrition
48. Contraceptives may contain _____.
a. estradiol only
b. luteinizing hormone only
c. estradiol only or progestin only
d. progestin only or a combination of estradiol and progestin
e. a combination of luteinizing hormone and progestin
ANSWER: d
49. Combination hormonal contraceptives are least likely to be associated with _____.
a. weight gain
b. decreased blood levels of HDL cholesterol
c. increased risk of blood clots
d. increased levels of triglycerides and LDL cholesterol
e. increased blood glucose and insulin
ANSWER: a
50. A woman would likely be advised to switch from a progestin-only hormonal contraceptive to a combination
hormonal contraceptive because of _____.
a. weight gain
b. irritability
c. fatigue
d. headache
e. abdominal pain
ANSWER: a
51. Which of the following glands secretes hormones?
a. seminal vesicle
b. bulbourethral gland
c. epididymis
d. oviduct
e. ovary
ANSWER: e
52. Women taking oral contraceptive pills are cautioned against _____.
a. consuming large amounts of animal products
b. consuming large amounts of carbohydrates
c. eating more than half a cup of peanut butter weekly
d. smoking
e. ingesting too much of vitamin B
ANSWER: d
53. The regular consumption of which of the following is recommended to improve iron deficiency?
a. sweet snacks
b. apricot
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Chapter 2 – Preconception Nutrition
c. lean meat
d. egg
e. rice
ANSWER: c
54. In a study done in California, women who received WIC services through to a subsequent pregnancy had _____ than
women who received WIC services only during their first pregnancy.
a. newborns with higher birth weights
b. greater risk of gestational diabetes
c. newborns with lower birth weights
d. newborns with lower birth lengths
e. higher blood glucose levels
ANSWER: a
55. Which of the following is an antioxidant?
a. vitamin E
b. vitamin B
c. iron
d. magnesium
e. glycol
ANSWER: a
56. In a study conducted in Vietnam, the offspring of women given multivitamin supplements before conception were less
likely to be stunted and had better fine motor skills at age 2 than women who received only _____ supplements.
a. iron
b. zinc
c. folic acid
d. retinoic acid
e. iodine
ANSWER: c
57. The National Academy of Nutrition and Dietetics has developed a set of standards called _____ to serve as guidelines
for the delivery of nutrition services.
a. the Nutrition Care Process
b. Supplemental Nutrition Program for Women, Infants, and Children
c. the preconception health services
d. the pregnancy health standards
e. the preconception nutrition guidelines
ANSWER: a
58. Which statement correctly describes preconception health care?
a. Preconception health care is concerned with the health and nutrition status of females only.
b. The psychological needs of pregnant females are not addressed as part of the preconception health care.
c. Fetal health and development is not a concern of preconception health care.
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d. Preconception health care may include topics such as vaccinations, weight status, and dietary intake.
e. Preconception health care advises couples about the most effective contraceptive methods to use.
ANSWER: d
Matching
Matching
a. The biological inability to bear children after one year of unprotected intercourse
b. The mass of tissue formed from the follicle after the egg is released
c. The biological ability to bear children
d. The actual production of children
e. The developing organism from 8 weeks to birth
f. The developing organism from conception to 8 weeks
g. The involuntary absence of production of children
h. Taking an unusually long time to conceive or having repeated pregnancy losses
i. The period in life in which humans become biologically capable of reproduction
j. The absence of a menstrual cycle
k. The loss of a conceptus in the first 20 weeks of pregnancy
59. Embryo
ANSWER: f
60. Fecundity
ANSWER: c
61. Subfertility
ANSWER: h
62. Fetus
ANSWER: e
63. Fertility
ANSWER: d
64. Infecundity
ANSWER: a
65. Miscarriage
ANSWER: k
66. Puberty
ANSWER: i
67. Corpus leteum
ANSWER: b
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68. Amenorrhea
ANSWER: j
69. Infertility
ANSWER: g
Subjective Short Answer
70. Describe the three types of individuals who would be considered subfertile.
ANSWER: Women who experience multiple miscarriages (variously defined as two or three), men who have sperm
abnormalities (such as low sperm count or density, malformed sperm, or immobile sperm), and women who
ovulate infrequently are considered subfertile.
71. Discuss the relationship between fertility, body weight, and body fat in females. Identify the possible implications
related to both inadequate and excessive body fat.
ANSWER: In normal-weight women, weight loss that exceeds approximately 10โ15 percent of usual weight decreases
estrogen, LH, and FSH concentrations. Consequences of these hormonal changes include amenorrhea,
anovulatory cycles, and short or absent luteal phases. It is estimated that about 30 percent of cases of
impaired fertility are related to simple weight loss. Hormone levels tend to return to normal when weight is
restored to within 95 percent of previous weight. Weight gain is the recommended first-line treatment for
amenorrhea related to low body weight.
Obese women tend to have higher levels of estrogen, androgens, and leptin than nonobese women. These
hormonal changes favor the development of menstrual-cycle irregularity (it occurs in 30โ47 percent of
overweight and obese women), ovulatory failure and anovulatory cycles, and amenorrhea. Loss of excess
body fat is related to improvements in hormone levels, oxidative stress and chronic inflammation, and
conception rates in both men and women. A critical level of body fat (usually indicated by a body mass
index over 20 kg/m2) is needed to trigger and sustain normal reproductive functions in women. Low level
of body fat during adolescence is related to delays in the age of onset of menstruation and to reduced
fertility later in life.
72. Describe the sources of disruptions in fertility in males and females.
ANSWER: The intricate mechanisms that regulate fertility can be disrupted by many factors, including adverse
nutritional exposures, severe stress, infection, tubal damage and other structural problems, and
chromosomal abnormalities. Conditions that modify fertility appear to affect hormones that regulate
ovulation, the presence or length of the luteal phase, sperm production, or the tubular passageways that ova
and sperm must travel for conception to occur. Sexually transmitted infections, for example, can result in
pelvic inflammatory disease (PID), which may lead to scarring and blockage of the fallopian tubes.
Endometriosis is also a common cause of reduced fertility. It develops when portions of the endometrial
wall that build up during menstrual cycles leave the uterus and become embedded within other body tissues.
Endocrine abnormalities that modify hormonal regulation of fertility are the leading diagnoses related to
infertility. “Unknown cause” is the next most common diagnosis, applied to about 10 percent of all cases of
male and female infertility.
73. Define pelvic inflammatory disease and explain its cause.
ANSWER: Pelvic inflammatory disease is a general term applied to infections of the cervix, uterus, fallopian tubes, or
ovaries. It occurs predominantly in young women and is generally caused by infection with a sexually
transmitted disease, such as gonorrhea or Chlamydia.
74. A couple trying to become pregnant for six months without success is seeking medical care. The man has a body mass
index of 28, and the woman has recently had irregular menses. During their medical visit, the woman mentioned that she
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had recently lost 10 pounds in a short time because she was worried about gaining too much weight during a future
pregnancy. What types of dietary or lifestyle behaviors would be important to discuss?
ANSWER: The man’s body mass index indicates that he may be overweight. Thus, he may be advised to eat a healthier
diet, follow nutritional guidelines, and exercise, because the loss of body fat is related to improvements in
hormone levels, oxidative stress and chronic inflammation, and conception rates. The woman’s irregular
menses after losing 10 pounds suggest that her weight loss may have negatively affected her fertility (as
sudden weight loss has been linked to decreased estrogen, LH, and FSH concentrations). Her irregular
menses, termed amenorrhea, may return to normal if her weight is restored to within 95 percent of her
previous weight. Through a healthy program of regaining weight and maintaining healthy activity, her
hormone levels may be returned to normal and her fertility improved.
75. Explain the mechanism of how contraceptive pills containing estradiol and progestin prevent pregnancy.
ANSWER: When used together, estradiol and progestin suppress the action of LH and FSH and thereby ovulation.
Progestin blocks LH and ovulation, and, by causing the cervical mucus to become thick and sticky, it induces
a barrier to sperm.
76. How might male reproductive health suffer because of inadequate intake of antioxidant nutrients?
ANSWER: Antioxidant nutrients are needed to protect cells of the reproductive system, including eggs and sperm, from
damage due to oxidative stress. Oxidative stress occurs when the production of potentially destructive
reactive oxygen molecules (free radicals) exceeds the body’s own antioxidant defenses. Reactive oxygen
molecules attack polyunsaturated fatty acids in sperm membranes, which decreases sperm motility and
reduces the ability of sperm to fuse with an egg. Once the membrane surrounding sperm is damaged, reactive
oxygen molecules can enter the sperm cell and damage DNA. This can result in the passage of defective
DNA.
77. Discuss the gene variant associated with folate status and its importance to periconceptional women.
ANSWER: Some individuals have an increased need for folate due to specific gene variants involved in folate
metabolism. These gene variants can impair the conversion of folate to its active form and increase folate
requirement. One of the best-studied and most common gene variants affects 5,10-methylenetetrahydrofolate
reductase (MTHFR) activity. This enzyme is responsible for production of the major circulating form of
folate used by the body. The C677T allele of the gene that encodes for MTHFR produces an enzyme that has
reduced activity. Women with this gene variant are at increased risk of having a neural tube defect-affected
newborn.
78. The Healthy People 2020 objectives related to infant health include reductions in preterm birth rates, incidence of
spina bifida, and neural tube defects. Define neural tube defects and describe the time frame for their development after
conception. Also, discuss any recommended behavioral or nutritional interventions important for women considering
pregnancy.
ANSWER: Neural tube defects (NTDs) are a group of birth defects that are caused by incomplete development of the
brain, spinal cord, or their protective coverings. Spina bifida is one of the most common types of NTDs.
NTDs develop between the third and fourth week after conceptionโor before many women even know they
are pregnant, and well before prenatal care generally begins. Folate is an essential nutrient required for DNA
replication and as a component of enzymatic reactions involved in amino acid synthesis and vitamin
metabolism. Knowledge of the folateโneural tube defect relationship, and awareness that folate intake was
inadequate in many women of childbearing age, prompted public health efforts to increase folate intake. In
particular, efforts are focused on encouraging women to consume folic acid, a highly absorbable, synthetic
form of this B vitamin. In 1998, the Food and Drug Administration mandated that refined grain products
such as white bread, grits, crackers, rice, and pasta be fortified with folic acid. Many countries now fortify
refined grain products with folic acid, and rates of NTDs have decreased significantly in these countries.
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Chapter 2 – Preconception Nutrition
79. What types of services are offered as part of preconceptional care?
ANSWER: Increasingly, routine preconceptional health care visits and educational sessions are being recommended
and introduced into health care services. Risk assessment services
focus on ascertainment of health history, dietary intake, folate and iron status, weight status, drug and
alcohol use, dietary supplement use, and vaccination status.
Psychosocial needs should also be addressed as part of preconceptional care, and referrals made to
appropriate services for issues such as eating disorders, abuse, violence, or lack of food or shelter.
80. List the four steps of the Nutrition Care Process.
ANSWER: The Nutrition Care Process consists of nutrition assessment, nutrition diagnosis, nutrition intervention, and
nutrition monitoring and evaluation.
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