Test Bank For Advanced Nutrition and Human Metabolism, 7th Edition Test Bank
Preview Extract
Chapter 02 The Digestive System Mechanism for Nourishing
the Body
MULTICHOICE
1. โWithin the lamina propria, lying just below the epithelium, is the mucosa-associated lymphoid
tissue (MALT), which ____.
(A) โcontrols secretions from the mucosal glands
(B) โcontains white blood cells and protects against ingested microorganisms
(C) โinitiates peristalsis
(D) โsecretes mucus, hormones, and digestive juices into the lumen
Answer : (B)
2. Which structural component of the gastrointestinal tract lies within the muscularis externa and
controls the contractions that cause motility?โ
(A) โmuscularis mucosae
(B) โsubmucosal plexus
(C) โmyenteric plexus
(D) โlumen
Answer : (C)
3. Which structure is not considered an accessory organ?โ
(A) โpancreas
(B) โliver
(C) โgallbladder
(D) โspleen
Answer : (D)
4. Bile is most important for the digestion and absorption of ____.โ
(A) โcarbohydrates
(B) โproteins
(C) โfats
(D) โvitamins
Answer : (C)
5. A decrease in the function of the parotid glands is most likely to result in ____.โ
(A) โa lack of triglyceride digestion
(B) โbolus that is difficult to form
(C) โsaliva that is too thin, that is, a high water to mucus ratio
(D) โdiarrhea due to malabsorption
Answer : (B)
6. โWhat is the name of the digestive enzyme in saliva that digests starch?
(A) โlipase
(B) โsynthetase
(C) โamylase
(D) โlactase
Answer : (C)
7. Which substance is not a component of saliva?โ
(A) โmucus
(B) โenzymes
(C) โwater
(D) โproteases
Answer : (D)
8. Endocrine cells of the pancreas are found in which structure?โ
(A) โthe pancreatic duct
(B) โthe islets of Langerhans
(C) โthe sphincter of Oddi
(D) โthe beta cells
Answer : (B)
9. Delayed gastric emptying is known as ____.โ
(A) โcholecystitis
(B) โcholelithiasis
(C) โgastritis
(D) โgastroparesis
Answer : (D)
10. โWhat product produced by neck cells in the oxyntic gland of the stomach protects the epithelium
from mechanical and chemical damage?
(A) โamylase
(B) โpepsin
(C) โgastrin
(D) โmucus
Answer : (D)
11. Which cells, found both in the oxyntic glands and pyloric glands of the stomach, secrete
hydrochloric acid and intrinsic factor?โ
(A) โneck cells
(B) โparietal cells
(C) โchief cells
(D) โenteroendocrine cells
Answer : (B)
12. Which cells, found in oxyntic glands in the body of the stomach, secrete pepsinogens?โ
(A) โneck cells
(B) โparietal cells
(C) โchief cells
(D) โenteroendocrine cells
Answer : (C)
13. โWhich specialized cell of the gastric epithelium secretes a hormone?
(A) โneck
(B) โparietal
(C) โchief
(D) โG-cell
Answer : (D)
14. The chief cells secrete ____.โ
(A) โgastrin
(B) โmucus
(C) โzymogens
(D) โhydrochloric acid
Answer : (C)
15. The parietal cells secrete ____.โ
(A) โhydrochloric acid and intrinsic factor
(B) โintrinsic factor and gastrin
(C) โgastrin and zymogens
(D) โzymogens and hydrochloric acid
Answer : (A)
16. Gastrin stimulates which cells?โ
(A) โoxyntic cells
(B) โparietal and chief cells
(C) โpancreatic exocrine cells
(D) โalpha cells
Answer : (B)
17. When the pH of the stomach is increased to avoid GERD, over time, the stomach may not be
acidic enough. What is the most likely outcome?โ
(A) โlack of carbohydrate digestion
(B) โdecreased protein digestion
(C) โdestruction of bacteria in the stomach
(D) โgastric ulcer
Answer : (B)
18. Which glycoproteins bind water and are gel-forming?โ
(A) โmucins
(B) โproteoglycans
(C) โprostaglandins
(D) โzymogens
Answer : (A)
19. โThe product(s) of pepsin’s action is/are ____.
(A) โdisaccharides
(B) โamylose
(C) โshort-chain fatty acids
(D) โhydrolyzed proteins
Answer : (D)
20. โPepcid, a drug that is classified as an H2 receptor blocker, acts by ____.
(A) โinhibiting the secretion of hydrogen ions by the parietal cells
(B) โinhibiting the release of acetylcholine by the vagus nerve
(C) โinhibiting the binding of gastrin to the parietal cells
(D) โinhibiting the binding of histamine to the parietal cells
Answer : (D)
21. โWhich medication inhibits hydrogen release into the gastric juice, which reduces GI mucosal
irritation?
(A) โPepcid
(B) โNexium
(C) โTums
(D) โTagamet
Answer : (B)
22. Which process allows gastric expansion with food intake with minimal impact on intragastric
pressure?โ
(A) โperistalsis
(B) โreceptive relaxation
(C) โsegmentation
(D) โpendular movement
Answer : (B)
23. Pyloric glands are located predominantly ____.โ
(A) โat the juncture of the esophagus and the stomach
(B) โin the fundus and the body of the stomach
(C) โin the antrum of the stomach
(D) โin the cardiac portion of the stomach
Answer : (C)
24. Which phrase best describes the function of the crypt of Lieberkรผhn?โ
(A) โmucus secretion
(B) โglucose oxidation
(C) โcellular differentiation
(D) โamylase secretion
Answer : (C)
25. The pancreas is a digestive system accessory organ with two types of active tissue-the ductless
endocrine cells that secrete insulin and glucagon and the ____.โ
(A) โliver-like cells that produce bile
(B) โductless absorptive tissue that controls bicarbonate
(C) โacinar exocrine cells that produce digestive enzymes
(D) โerythropoietic cells that produce red blood cells
Answer : (C)
26. Pancreatic juice that enters the duodenum through the sphincter of Oddi contains all of the
following EXCEPT ____.โ
(A) โdigestive enzymes
(B) โintrinsic factor
(C) โanions such as bicarbonate and chloride
(D) โcations such as sodium, potassium, and calcium
Answer : (B)
27. In which part of the brain is the swallowing center located?โ
(A) โthe hypothalamus
(B) โthe medulla oblongata
(C) โthe thalamus
(D) โthe pons
Answer : (B)
28. In which organ are enzymes produced that are responsible for digestion of 50 percent of
carbohydrate and protein and 90 percent of fat?โ
(A) โliver
(B) โesophagus
(C) โpancreas
(D) โgallbladder
Answer : (C)
29. Which hormone’s major action is to alkalize intestinal contents by stimulating secretion of
bicarbonate from the pancreas and by inhibiting gastric acid secretion and gastric emptying?โ
(A) โgastrin
(B) โsecretin
(C) โcholecystokinin
(D) โGRP
Answer : (B)
30. Dumping syndrome may be caused by ____.โ
(A) โbacterial infections
(B) โviral infections
(C) โpartial removal of the stomach to treat obesity
(D) โgall stones
Answer : (C)
31. The hormone primarily responsible for contraction of the gallbladder and release of bile into the
duodenum is ____.โ
(A) โgastrin
(B) โsecretin
(C) โcholecystokinin
(D) โGRP
Answer : (C)
32. Bile salts are synthesized from cholesterol in the ____.โ
(A) โcanaliculi
(B) โcommon bile duct
(C) โhepatocytes
(D) โgallbladder
Answer : (C)
33. The surface coat of microvilli is known as ____.โ
(A) โthe glycocalyx
(B) โthe crypts of Lieberkรผhn
(C) โmotilin
(D) โproteases
Answer : (A)
34. The total bile acid pool in the human body is 2.5 to 5 g. What percentage of bile is reabsorbed in
the distal ileum?โ
(A) โ10 percent
(B) โ30 percent
(C) โ65 percent
(D) โ90 percent
Answer : (D)
35. A large gall stone blocking the cystic duct might result in ____.โ
(A) โa reduction in the production of bile by the liver
(B) โan increase in bile production by the liver
(C) โenhancement of fat digestion
(D) โinterference with fat digestion
Answer : (D)
36. Which substance is enterohepatically circulated?โ
(A) โpancreatic enzymes
(B) โbile
(C) โglucose
(D) โCCK
Answer : (B)
37. In general, in which portion of the gastrointestinal tract does most absorption occur?โ
(A) โesophagus
(B) โstomach
(C) โsmall intestine
(D) โcolon
Answer : (C)
38. A common cause of peptic ulcer disease (PUD) is the bacterium ____.โ
(A) โEscherichia coli
(B) โHelicobacter pylori
(C) โStaphylococcus aureus
(D) โEnterobacter aerogenes
Answer : (B)
39. Which structure helps to prevent the migration of bacteria from the large intestine back into the
small intestine?โ
(A) โthe cecum
(B) โthe appendix
(C) โthe ileocecal valve
(D) โthe ileum
Answer : (C)
40. Which hormone(s) is/are responsible for decreasing sodium absorption in the colon?โ
(A) โglucocorticoids
(B) โmineralocorticoids
(C) โvasopressin
(D) โglucagon
Answer : (C)
41. Which division of the nervous system decreases digestive tract motility and secretions?โ
(A) โparasympathetic
(B) โsomatic
(C) โadrenergic
(D) โsympathetic
Answer : (D)
42. Which hormone diminishes gastric acid secretion?โ
(A) โsomatostatin
(B) โgastrin
(C) โcholecystokinin
(D) โpancreatic polypeptide
Answer : (A)
43. Which hormone stimulates gall bladder contraction?โ
(A) โmotilin
(B) โgastrin
(C) โcholecystokinin
(D) โsecretin
Answer : (C)
44. A deficiency in secretion of cholecystokinin might lead to which problem?โ
(A) โa reduction in gastric acid production
(B) โdifficulty digesting fats
(C) โdifficulty digesting proteins
(D) โa buildup of intestinal gas
Answer : (B)
45. When diagnosing lactose intolerance, ____ is measured in the breath following oral consumption
of 50 g lactose.โ
(A) โmethane
(B) โhydrogen
(C) โcarbon dioxide
(D) โsulfur
Answer : (B)
46. Lactose intolerance is least common in _____.โ
(A) โEuropean Americans
(B) โAfrican Americans
(C) โAmerican Indians
(D) โAsian Americans
Answer : (A)
47. Taking antihistamines might lead to a(n) ____.โ
(A) โincrease in stomach acid production
(B) โincrease in bile release
(C) โdecrease in stomach acid secretion
(D) โreduction in pancreatic enzyme production
Answer : (C)
48. Which hormone decreases appetite?โ
(A) โpeptide YY
(B) โmotilin
(C) โsecretin
(D) โpancreatic polypeptide
Answer : (A)
49. Among the regulatory peptide molecules, some are recognized as true hormones. Which
substance is a paracrine rather than a hormone?โ
(A) โsomatostatin
(B) โsecretin
(C) โcholecystokinin
(D) โgastrin
Answer : (A)
50. Secretin is released from the enteroendocrine S-cell in the ____.โ
(A) โproximal small intestine
(B) โgastric mucosa
(C) โesophagus
(D) โcolon
Answer : (A)
TRUEFALSE
51. โSecretin stimulates HCl release.
(A) True
(B) False
Answer : (B)
52. CCK stimulates pancreatic zymogen release.โ
(A) True
(B) False
Answer : (A)
53. Leptin secretion stimulates the desire to eat.โ
(A) True
(B) False
Answer : (B)
54. CCK stimulates the release of bile.โ
(A) True
(B) False
Answer : (A)
55. GIP stimulates the release of a hormone from the pancreatic ฮฒ-cells.โ
(A) True
(B) False
Answer : (A)
56. Eating a meal stimulates ghrelin secretion.โ
(A) True
(B) False
Answer : (B)
57. Ghrelin increases satiety.โ
(A) True
(B) False
Answer : (B)
58. Gastrin stimulates gastric acid secretion.โ
(A) True
(B) False
Answer : (A)
59. โPeptide YY stimulates gastric acid secretion.
(A) True
(B) False
Answer : (B)
60. Secretin stimulates gastric emptying.โ
(A) True
(B) False
Answer : (B)
61. โShort-chain fatty acids secreted by intestinal bacteria improve colonic and splanchnic blood
flow.
(A) True
(B) False
Answer : (A)
62. The predominant component of saliva is amylase.โ
(A) True
(B) False
Answer : (B)
63. โThe fundus of the stomach lies below the gastroesophageal sphincter.
(A) True
(B) False
Answer : (B)
64. Villi are s-designed to increase the absorptive surface area of the smallโ
(A) True
(B) False
Answer : (A)
65. Pancreatitis occurs when zymogens become activated within theโ pancreas.
(A) True
(B) False
Answer : (A)
MATCH
66. โDigestive Substances: Match the substance important for digestion with its site of production.
MATCH
67. Match the corresponding action to the hormone. Each choice is used only once.โ
SHORTANSWER
68. โDiscuss the role of drug therapies such as Tagamet, Zantac, and Pepcid in the treatment of
peptic ulcers.Answer : The answer should include the following items:
69. โDescribe the beneficial effects of secretions released by colonic bacteria.Answer : The answer
should include the following items:
70. What happens to reabsorbed bile acids after transported back to the liver?โAnswer : The answer
should include the following items:
Answer : Reabsorbed bile acids are reconjugated to amino acids and secreted into bile along with
the newly synthesized bile acids.
71. โDescribe the mechanisms by which resin-type drugs and functional foods containing
phytostanols lower high blood cholesterol levels.Answer : The answer should include the following
items:
72. Broad-spectrum antibiotics are capable of killing many different bacteria, including many of
those that naturally live in the intestines. Develop a hypothesis regarding the effects of broadspectrum antibiotics on the beneficial effects of gut flora.โAnswer : The answer should include the
following items:
73. What are probiotics and prebiotics? Give examples of each.โAnswer : The answer should include
the following items:
Answer : Probiotics are live microorganisms (that is, active cultures of specific strains of bacteria)
that when administered in adequate amounts confer health benefits to its hosts. Prebiotics
(discussed in more detail in Chapter 4) are substances that are not digested by human digestive
enzymes but confer health benefits to the host by acting as substrates for the growth and/or activity
of one or more species of healthful bacteria in the colon.
Answer : The most common probiotic bacteria are lactic acid bacteria, usually strains of
Lactobacillus and Bifidobacterium genera. To be considered a probiotic, the product must contain
100 million live active bacteria per gram. At present, probiotics are mostly consumed as yogurt with
live cultures and as fermented or cultured milk and milk products (such as buttermilk and kefir). In
the United States, yogurt is often fermented by Lactobacillus bulgaricus and Streptococcus
thermophilus, and milk is usually fermented by L. acidophilus and L. casei. Other bacteria used to
manufacture dairy products include Leuconostoc esntheroides, L. mesenteroides, and Lactococcus
lactis. Other food sources of probiotics include miso, tempeh, and some soy beverages/products.
74. Discuss three of the five mechanisms by which probiotics may be helpful in diarrheal
illnesses.โAnswer : The answer should include three of the following items:
75. โHow might an imbalance of the hormones ghrelin and leptin lead to obesity?Answer : The
answer should include the following items:
Answer : Because ghrelin acts on the hypothalamus to stimulate appetite, and leptin suppresses
food intake, an imbalance could affect an individualโs ability to control his or her appetite leading to
obesity.
76. โBariatric surgery involves removal or bypass of a large portion of the stomach. Speculate on how
the production of ghrelin following bariatric surgery might affect appetite and explain your
reasoning.Answer : The answer should include the following items:
77. Discuss the functions and significance of the folds of Kerckring, the villi, and the
microvilli.โAnswer : The answer should include the following items:
MULTICHOICE
78. โRYGB surgery involves ____.
(A) โcreating a pouch after the proximal and distal portions of the stomach are separated
(B) โplacing a band on the stomach and creating a pouch
(C) โremoving 85 percent of the stomach surgically
(D) โconnecting the esophagus directly to the duodenum
Answer : (A)
79. The most common bariatric procedure performed in the United States is ____.โ
(A) โgastric banding
(B) โsleeve gastrectomy
(C) โRYGB
(D) โbiliopancreatic diversion
Answer : (C)
80. Which nutritional deficiency occurs frequently following RYGB?โ
(A) โvitamin D
(B) โprotein
(C) โfat
(D) โvitamin C
Answer : (B)
81. Deficiency of which vitamin is associated with neurological deficiencies?โ
(A) โvitamin D
(B) โvitamin C
(C) โvitamin A
(D) โthiamin
Answer : (D)
82. Deficiency of vitamin B12 occurs due to ____.โ
(A) โinflammation of the GI tract
(B) โinsufficient intrinsic factor
(C) โa change in diet
(D) โexcessive stomach acid
Answer : (B)
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