Preview Extract
Human Anatomy & Physiology, 10e, (Marieb)
Chapter 2 Chemistry Comes Alive
2.1 Matching Questions
Figure 2.1
Using Figure 2.1, match the following:
A) C
B) B
C) E
D) D
E) A
1) Lipid.
Section: 2.9
Learning Outcome: 2.18
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
2) Functional protein.
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
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3) Nucleotide.
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
4) Polysaccharide.
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
5) Monosaccharide.
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
6) Polymer.
Section: 2.7, 2.8
Learning Outcome: 2.16, 2.17
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 2 Comprehension
7) Tertiary (protein) structure.
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
Answers: 1) D 2) B 3) C 4) A 5) E6) A 7) B
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Figure 2.2
Using Figure 2.2, match the following:
A) A
B) D
C) B
D) E
E) C
8) Deoxyribose sugar.
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
9) Thymine.
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 2 Comprehension
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10) Guanine.
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 2 Comprehension
11) Phosphate.
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 1 Knowledge
12) Hydrogen bonds.
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS2
Bloom’s Level: 2 Comprehension
Answers: 8) C 9) B 10) D 11) E 12) A
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Match the following chemical bonds to the correct description:
A)Nonpolar covalent bond
B)Polar covalent bond
C) Ionic bond
D) Hydrogen bond
13) A bond in which electrons are shared unequally.
Section: 2.4
Learning Outcome: 2.10
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
14) A bond in which electrons are completely lost or gained by the atoms involved.
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
15) A bond in which electrons are shared equally.
Section: 2.4
Learning Outcome: 2.10
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
16) A type of bond important in tying different parts of the same molecule together into a threedimensional structure.
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
Answers: 13) B 14) C 15) A 16) D
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Match the following particles to the correct description:
A)Atom
B)Nuetron
C) Cation
D) Molecule
17) Electrically charged particle due to loss of an electron.
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
18) Neutral subatomic particle.
Section: 2.2
Learning Outcome: 2.4
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
19) Smallest particle of an element that retains its properties.
Section: 2.2
Learning Outcome: 2.4
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
20) Combination of two or more atoms of the same element held together by chemical bonds.
Section: 2.3
Learning Outcome: 2.6
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
Answers: 17) C 18) B 19) A 20) D
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Match the following:
A) Compound
B) Mixture
C) Element
21) Water.
Section: 2.3
Learning Outcome: 2.6
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
22) Carbon.
Section: 2.2
Learning Outcome: 2.3
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
23) Dry ice (frozen carbon dioxide).
Section: 2.3
Learning Outcome: 2.6
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
24) Blood.
Section: 2.3
Learning Outcome: 2.6
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
Answers: 21) A 22) C 23) A 24) B
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Match the following:
A)Weight
B)Mass
C) Matter
D) Energy
25) Can be measured only by its effects on matter.
Section: 2.1
Learning Outcome: 2.1
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
26) Anything that occupies space and has mass.
Section: 2.1
Learning Outcome: 2.1
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
27) Although a man who weighs 175 pounds on Earth would be lighter on the moon and heavier
on Jupiter, his ________ would not be different.
Section: 2.1
Learning Outcome: 2.1
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
28) Is a function of, and varies with, gravity.
Section: 2.1
Learning Outcome: 2.1
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
Answers: 25) D 26) C 27) B 28) A
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Match the following:
A)Mechanical energy
B)Chemical energy
C) Electrical energy
D) Radiant energy
29) Legs moving the pedals of a bicycle.
Section: 2.1
Learning Outcome: 2.2
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
30) When the bonds of ATP are broken, energy is released to do cellular work.
Section: 2.1
Learning Outcome: 2.2
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
31) Energy that travels in waves. Part of the electromagnetic spectrum.
Section: 2.1
Learning Outcome: 2.2
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
32) Represented by the flow of charged particles along a conductor, or the flow of ions across a
membrane.
Section: 2.1
Learning Outcome: 2.2
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
Answers: 29) A 30) B 31) D 32) C
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Match the following:
A) Solutions
B) Suspensions
C) Colloids
33) Heterogeneous, will not settle.
Section: 2.3
Learning Outcome: 2.7
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
34) Heterogeneous, will settle.
Section: 2.3
Learning Outcome: 2.7
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
35) Homogeneous, will not settle.
Section: 2.3
Learning Outcome: 2.7
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
36) Will not scatter light.
Section: 2.3
Learning Outcome: 2.7
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
Answers: 33) C 34) B 35) A 36) A
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Match the following:
A)Atomic symbol
B)Mass number of an element
C) Atomic number
37) Usually, the first one or two letters of an element’s name.
Section: 2.2
Learning Outcome: 2.4
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
38) Number of protons in an atom.
Section: 2.2
Learning Outcome: 2.5
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
39) Combined number of protons and neutrons in an atom.
Section: 2.2
Learning Outcome: 2.5
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
Answers: 37) A 38) C 39) B
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2.2 True/False Questions
1) The atomic weight is an average of the relative weights (mass numbers) of all the isotopes of
an element.
Answer: TRUE
Section: 2.2
Learning Outcome: 2.5
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
2) It is the difference in the R group that makes each amino acid chemically unique.
Answer: TRUE
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
3) Chemical properties are determined primarily by neutrons.
Answer: FALSE
Section: 2.4
Learning Outcome: 2.8
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
4) A charged particle is generally called an ion or electrolyte.
Answer: TRUE
Section: 2.6
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
5) Isotopes differ from each other only in the number of electrons the atom contains.
Answer: FALSE
Section: 2.2
Learning Outcome: 2.5
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
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6) About 60% to 80% of the volume of most living cells consists of organic compounds.
Answer: FALSE
Section: 2.6
Learning Outcome: 2.14
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
7) Triglycerides are a poor source of stored energy.
Answer: FALSE
Section: 2.9
Learning Outcome: 2.18
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
8) Omega-3 fatty acids appear to decrease the risk of heart disease.
Answer: TRUE
Section: 2.9
Learning Outcome: 2.18
Global LO: G2, G5
HAPS LO: HAPS1, HAPS6
Bloom’s Level: 1 Knowledge
9) Glucose is an example of a monosaccharide.
Answer: TRUE
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
10) Glycogen, the storage form of glucose, is primarily stored in skeletal muscle and liver cells.
Answer: TRUE
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
11) The lower the pH, the higher the hydrogen ion concentration.
Answer: TRUE
Section: 2.6
Learning Outcome: 2.15
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
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12) Covalent bonds are generally less stable than ionic bonds.
Answer: FALSE
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
13) Hydrogen bonds are too weak to bind atoms together to form molecules, but they do hold
different parts of a single large molecule in a specific three-dimensional shape.
Answer: TRUE
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
14) The fact that no chemical bonding occurs between the components of a mixture is the chief
difference between mixtures and compounds.
Answer: TRUE
Section: 2.3
Learning Outcome: 2.6
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
15) The acidity of a solution reflects the concentration of free hydrogen ions in the solution.
Answer: TRUE
Section: 2.6
Learning Outcome: 2.15
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
16) A chemical bond is an energy relationship between outer electrons and neighboring atoms.
Answer: TRUE
Section: 2.4
Learning Outcome: 2.8
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
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17) All organic compounds contain carbon.
Answer: TRUE
Section: 2.7
Learning Outcome: 2.16
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
18) A dipeptide can be broken into two amino acids by dehydration synthesis.
Answer: FALSE
Section: 2.7
Learning Outcome: 2.16
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
19) The pH of body fluids must remain fairly constant for the body to maintain homeostasis.
Answer: TRUE
Section: 2.6
Learning Outcome: 2.15
Global LO: G2
HAPS LO: HAPS1, HAPS3
Bloom’s Level: 1 Knowledge
20) Mixtures are combinations of elements or compounds that are physically blended together
but are not bound by chemical bonds.
Answer: TRUE
Section: 2.3
Learning Outcome: 2.6
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
21) Buffers resist abrupt and large changes in the pH of body fluids by releasing or binding ions.
Answer: TRUE
Section: 2.6
Learning Outcome: 2.15
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
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1.3 Multiple Choice Questions
1) The basic structural material of the body consists of ________.
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
Answer: A
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
2) In general, the lipids that we refer to as oils have ________.
A) long fatty acid chains
B) a high water content
C) unsaturated fatty acids
D) saturated fatty acids
Answer: C
Section: 2.9
Learning Outcome: 2.18
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
3) The genetic information is coded in DNA by the ________.
A) sequence of the nucleotides
B) three-dimensional structure of the double helix
C) arrangement of the histones
D) regular alteration of sugar and phosphate molecules
Answer: A
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
4) Which of the following does NOT characterize proteins?
A) Their function depends on their three-dimensional shape.
B) They may be denatured or coagulated by heat or acidity.
C) They appear to be the molecular carriers of coded hereditary information.
D) They have both functional and structural roles in the body.
Answer: C
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
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HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
5) The single most abundant protein in the body is ________.
A) hemoglobin
B) collagen
C) DNA
D) glucose
Answer: B
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
6) Carbohydrates are stored in the liver and skeletal muscles in the form of ________.
A) triglycerides
B) glycogen
C) glucose
D) cholesterol
Answer: B
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
7) Which of the following does NOT describe enzymes?
A) Enzymes work by raising the energy of activation.
B) Some enzymes are purely protein.
C) Some enzymes are protein plus a cofactor.
D) Each enzyme is chemically specific.
Answer: A
Section: 2.10
Learning Outcome: 2.20
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
8) Which of the following is a general function for a fibrous protein?
A) protein management
B) transport
C) structural framework
D) body defense
E) catalysis
Answer: C
Section: 2.10
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Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
9) Salts are always ________.
A) double covalent compounds
B) single covalent compounds
C) ionic compounds
D) hydrogen bonded
Answer: C
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
10) The numbers listed represent the number of electrons in the first, second, and third energy
levels, respectively. On this basis, which of the following is an unstable or reactive atom?
A) 2
B) 2, 8
C) 2, 8, 1
D) 2, 8, 8
Answer: C
Section: 2.4
Learning Outcome: 2.8
Global LO: G2, G4
HAPS LO: HAPS1, HAPS4
Bloom’s Level: 3 Application
11) Which of the following statements is FALSE?
A) The pH of blood is slightly basic.
B) The more hydrogen ions in a solution, the more acidic the solution.
C) When acids and bases are mixed, they react with each other to form water and a salt.
D) When the hydrogen ion concentration decreases, the hydroxyl ion concentration also
decreases.
Answer: D
Section: 2.6
Learning Outcome: 2.15
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
12) Which of the following is the major positive ion outside cells?
A) hydrogen
B) magnesium
C) sodium
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D) potassium
Answer: C
Section: 2.2
Learning Outcome: 2.3
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
13) Which of the following would be regarded as an organic molecule?
A) NaCl
B) H2O
C) CH4
D) NaOH
Answer: C
Section: 2.7
Learning Outcome: 2.16
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 3 Application
14) What is a chain of more than 50 amino acids called?
A) protein
B) triglyceride
C) nucleic acid
D) polysaccharide
Answer: A
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
15) What structural level is represented by the coiling of the protein chain backbone into an
alpha helix?
A) tertiary structure
B) secondary structure
C) primary structure
D) quaternary structure
Answer: B
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
16) Carbohydrates and proteins are built up from their basic building blocks by the ________.
A) addition of a carbon atom between each two units
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B) removal of a water molecule between each two units
C) addition of a water molecule between each two units
D) removal of a carbon atom between each two units
Answer: B
Section: 2.7
Learning Outcome: 2.16
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
17) Which statement about enzymes is FALSE?
A) Most enzymes can catalyze millions of reactions per minute.
B) Enzymes may be damaged by high temperature.
C) Enzymes may use coenzymes derived from vitamins or cofactors from metallic elements.
D) Enzymes require contact with substrate in order to assume their active form.
Answer: D
Section: 2.10
Learning Outcome: 2.20
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
18) Which of the following statements is FALSE?
A) Chemical reactions progress at a faster rate when the reacting particles are present in higher
numbers.
B) Catalysts increase the rate of chemical reactions, sometimes while undergoing reversible
changes in shape.
C) Larger particles move faster than smaller ones and thus collide more frequently and more
forcefully.
D) Chemical reactions proceed more quickly at higher temperatures.
Answer: C
Section: 2.5
Learning Outcome: 2.13
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
19) Choose the answer that best describes HCO3-.
A) a proton donor
B) a weak acid
C) a bicarbonate ion
D) common in the liver
Answer: C
Section: 2.6
Learning Outcome: 2.15
Global LO: G2
HAPS LO: HAPS1
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Bloom’s Level: 2 Comprehension
20) What happens in redox reactions?
A) the electron acceptor is oxidized
B) the organic substance that loses hydrogen is usually reduced
C) both decomposition and electron exchange occur
D) the reaction is uniformly reversible
Answer: C
Section: 2.5
Learning Outcome: 2.11
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
21) Choose the answer that best describes fibrous proteins.
A) rarely exhibit secondary structure
B) are usually called enzymes
C) are cellular catalysts
D) are very stable and insoluble in water
Answer: D
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
22) Which of the following does NOT describe uses for the ATP molecule?
A) pigment structure
B) mechanical work
C) transport across membranes
D) chemical work
Answer: A
Section: 2.12
Learning Outcome: 2.22
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
23) Which of the following is an example of a suspension?
A) salt water
B) rubbing alcohol
C) blood
D) cytosol
Answer: C
Section: 2.3
Learning Outcome: 2.7
Global LO: G2
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HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
24) Select the correct statement about isotopes.
A) All the isotopes of an element have the same number of neutrons but differing numbers of
electrons.
B) Isotopes of the same element have the same atomic number but differ in their mass number.
C) All the isotopes of an element are radioactive.
D) Isotopes occur only in the heavier elements.
Answer: B
Section: 2.2
Learning Outcome: 2.5
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
25) The four elements that make up about 96% of body weight are ________.
A) carbon, oxygen, hydrogen, nitrogen
B) carbon, oxygen, phosphorus, calcium
C) nitrogen, hydrogen, calcium, sodium
D) sodium, potassium, hydrogen, oxygen
Answer: A
Section: 2.2
Learning Outcome: 2.3
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
26) ________ is fat soluble, produced in the skin on exposure to UV radiation, and necessary for
normal bone growth and function.
A) Cortisol
B) Vitamin K
C) Vitamin A
D) Vitamin D
Answer: D
Section: 2.9
Learning Outcome: 2.18
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
27) Atom X has 17 protons. How many electrons are in its valence shell (outermost energy
level)?
A) 7
B) 3
C) 5
D) 10
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Answer: A
Section: 2.4
Learning Outcome: 2.8
Global LO: G2, G4
HAPS LO: HAPS1
Bloom’s Level: 3 Application
28) A high fever causes an enzyme to lose its three dimensional structure and function. Which
bonds are broken when a protein denatures?
A) non-polar covalent bonds
B) polar covalent bonds
C) ionic bonds
D) hydrogen bonds
Answer: D
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 3 Application
29) If atom X has an atomic number of 74 it would have which of the following?
A) 37 protons and 37 neutrons
B) 37 protons and 37 electrons
C) 37 electrons
D) 74 protons
Answer: D
Section: 2.2
Learning Outcome: 2.5
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 3 Application
30) What does the formula C6H12O6 mean?
A) The substance is a colloid.
B) There are 6 calcium, 12 hydrogen, and 6 oxygen atoms.
C) The molecular weight is 24.
D) There are, 6 carbon, 12 hydrogen, and 6 oxygen atoms.
Answer: D
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
31) An atom with 3 electrons in its outermost (valence) shell may have a total of ________
electrons altogether.
A) 13
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B) 8
C) 17
D) 3
Answer: A
Section: 2.4
Learning Outcome: 2.8
Global LO: G2, G4
HAPS LO: HAPS1
Bloom’s Level: 3 Application
32) Which of the following is a neutralization reaction?
A) NH3 + H+ โ NH4+2
B) HCl + NaOH โ NaCl + H2O
C) HCl โ H+ + ClD) NaOH โ Na+ + OHAnswer: B
Section: 2.6
Learning Outcome: 2.15
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
33) The chemical symbol O=O means ________.
A) the atoms are double bonded
B) both atoms are bonded and have zero electrons in the outer orbit
C) zero equals zero
D) this is an ionic bond with two shared electrons
Answer: A
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
34) What is a dipole?
A) a polar molecule
B) an organic molecule
C) a type of reaction
D) a type of bond
Answer: A
Section: 2.4
Learning Outcome: 2.10
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
35) What does CH4 mean?
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A) This is an inorganic molecule.
B) This was involved in a redox reaction.
C) There is one carbon and four hydrogen atoms.
D) There are four carbon and four hydrogen atoms.
Answer: C
Section: 2.3
Learning Outcome: 2.6
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
36) Amino acids joining together to make a peptide is a good example of a(n) ________
reaction.
A) decomposition
B) reversible
C) synthesis
D) exchange
Answer: C
Section: 2.5
Learning Outcome: 2.11
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
37) Which of the following is NOT considered a factor in influencing a reaction rate?
A) time
B) concentration of reactants
C) temperature
D) particle size
Answer: A
Section: 2.5
Learning Outcome: 2.13
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
38) Which property of water is demonstrated when we sweat?
A) high heat of vaporization
B) polar solvent properties
C) high heat capacity
D) reactivity
E) cushioning
Answer: A
Section: 2.6
Learning Outcome: 2.14
Global LO: G2
HAPS LO: HAPS1, HAPS3
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Bloom’s Level: 2 Comprehension
39) Sucrose is a ________.
A) disaccharide
B) polysaccharide
C) triglyceride
D) monosaccharide
Answer: A
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
40) What is the ratio of fatty acids to glycerol in triglycerides (neutral fats)?
A) 4:1
B) 3:1
C) 1:1
D) 2:1
Answer: B
Section: 2.9
Learning Outcome: 2.18
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
41) In a DNA molecule, the phosphate serves ________.
A) as a code
B) to hold the molecular backbone together
C) as nucleotides
D) to bind the sugars to their bases
Answer: B
Section: 2.11
Learning Outcome: 2.21
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 1 Knowledge
42) When frying an egg, the protein albumin denatures and maintains only its ________
structure.
A) tertiary
B) secondary
C) quaternary
D) primary
Answer: D
Section: 2.10
Learning Outcome: 2.19
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Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 4 Analysis
43) Which of the following is chemically inert (unreactive)?
A) carbon (atomic number 6)
B) oxygen (atomic number 8)
C) neon (atomic number 10)
D) sodium (atomic number 11)
Answer: C
Section: 2.4
Learning Outcome: 2.8
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 4 Analysis
44) An atom with an atomic number of 10 and a mass number of 24 would have ________.
A) 14 electrons
B) 14 neutrons
C) 24 protons
D) 10 neutrons
Answer: B
Section: 2.2
Learning Outcome: 2.5
Global LO: G2, G4
HAPS LO: HAPS1
Bloom’s Level: 4 Analysis
45) When DNA is replicated, it is necessary for the two strands to “unzip” temporarily. Choose
which bonding type is most appropriate for holding the strands together in this way.
A) non-polar covalent bonding
B) hydrogen bonding
C) ionic bonding
D) polar covalent bonding
Answer: B
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 3 Application
46) Lithium has an atomic number of 3. How many electrons are there in the outermost (valence)
shell?
A) one
B) two
C) zero
D) three
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Answer: A
Section: 2.4
Learning Outcome: 2.8
Global LO: G2, G4
HAPS LO: HAPS1
Bloom’s Level: 4 Analysis
47) ATP โ ADP + Pi is an example of a(n) ________ reaction.
A) decomposition
B) exchange
C) synthesis
D) reversible
Answer: A
Section: 2.5
Learning Outcome: 2.11
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 3 Application
48) An acid with a pH of 6 has ________ hydrogen ions than pure water.
A) 100-fold fewer
B) 10-fold more
C) 10-fold fewer
D) 100-fold more
Answer: B
Section: 2.6
Learning Outcome: 2.15
Global LO: G2, G4
HAPS LO: HAPS1
Bloom’s Level: 3 Application
49) A patient is hyperventilating. The “blowing off” of excessive carbon dioxide causes a
decrease in blood H+ concentration. How can the carbonic acid-bicarbonate buffer system
function to correct this imbalance?
CO2 + H2O โ H2CO3 โ H+ + HCO3A) HCO3- binds with H+ to form H2CO3 and lower pH
B) HCO3- binds with H+ to form H2CO3 and raise pH
C) H2CO3 dissociates to form more H+ and lower pH
D) H2CO3 dissociates to form more H+ and raise pH
Answer: C
Section: 2.6
Learning Outcome: 2.15
Global LO: G2, G7
HAPS LO: HAPS1, HAPS6
Bloom’s Level: 4 Analysis
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50) Forming glycogen as energy storage in the liver is an example of ________.
A) exergonic
B) anabolism
C) catabolism
D) oxidation
Answer: B
Section: 2.5
Learning Outcome: 2.11
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 3 Application
51) Salivary amylase is an enzyme produced by the salivary glands that breaks down
carbohydrates. What will happen to this enzyme as it follows the food into the stomach where
the pH drops to 2.5?
A) The enzyme will assume an alternate form and catalyze additional reactions.
B) The enzyme will denature and become inactive.
C) The enzyme will continue to function as it remains unchanged in chemical reactions.
D) The enzyme will denature but retain its function.
Answer: B
Section: 2.10
Learning Outcome: 2.20
Global LO: G2, G7
HAPS LO: HAPS1, HAPS4
Bloom’s Level: 3 Application
52) With a family history of cardiovascular disease, which toast spread would be considered the
most “heart healthy?”
A) olive oil
B) butter containing butterfat
C) lard (pig fat)
D) margarine containing trans fats
Answer: A
Section: 2.9
Learning Outcome: 2.18
Global LO: G2, G5
HAPS LO: HAPS1, HAPS6
Bloom’s Level: 3 Application
53) Which of the following is incorrectly matched?
A) monosaccharide; carbohydrate
B) eicosanoid; triglyceride
C) amino acid; protein
D) nucleotide; nucleic acid
Answer: B
Section: 2.9
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Learning Outcome: 2.18
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 3 Application
54) Starch is the stored carbohydrate in plants, while ________ is the stored carbohydrate in
animals.
A) glycogen
B) cellulose
C) triglyceride
D) glucose
Answer: A
Section: 2.8
Learning Outcome: 2.17
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
55) How many phosphates would AMP have attached to it?
A) three
B) two
C) one
D) none
Answer: C
Section: 2.12
Learning Outcome: 2.22
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 2 Comprehension
56) Tendons are strong, rope-like structures that connect skeletal muscle to bone. Which of the
following proteins would provide strength to a tendon?
A) albumin
B) molecular chaperone
C) actin
D) collagen
Answer: D
Section: 2.10
Learning Outcome: 2.19
Global LO: G2
HAPS LO: HAPS1, HAPS4
Bloom’s Level: 3 Application
57) Phospholipids make up most of the lipid part of the cell membrane. Since water exists on
both the outside and inside of a cell, which of the following phospholipid arrangements makes
the most sense?
A) a single layer of phospholipids with the polar heads facing outside the cell
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Copyright ยฉ 2016 Pearson Education, Ltd.
B) a single layer of phospholipids with the polar heads facing inside the cell
C) two back-to-back phospholipid layers with the polar heads facing out on both sides
D) two back-to-back phospholipid layers with the non-polar tails facing out on both sides
Answer: C
Section: 2.9
Learning Outcome: 2.18
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 4 Analysis
58) What type of chemical bond can form between an atom with 11 protons and an atom with 17
protons?
A) polar covalent
B) ionic
C) non-polar covalent
D) hydrogen
Answer: B
Section: 2.4
Learning Outcome: 2.9
Global LO: G2
HAPS LO: HAPS1
Bloom’s Level: 4 Analysis
1.4 Short Answer Questions
1) What happens when globular proteins are denatured?
Answer: The active sites are destroyed.
Section: 2.10
Learning Outcome: 2.19
Global LO: G2, G8
HAPS LO: HAPS1, HAPS4, HAPS11
Bloom’s Level: 2 Comprehension
2) Explain the difference between potential and kinetic energy.
Answer: Potential energy is inactive stored energy that has potential to do work. Kinetic energy
is energy in action.
Section: 2.1
Learning Outcome: 2.1
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
3) How can phospholipids form a film when mixed in water?
Answer: Phospholipids have both polar and nonpolar ends. The polar end interacts with water,
leaving the nonpolar end oriented in the opposite direction.
Section: 2.9
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Learning Outcome: 2.18
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
4) What advantages does ATP have in being the energy currency molecule?
Answer: Its energy is easy to capture and store; it releases just the right amount of energy for the
cell’s needs so it is protected from excessive energy release. A universal energy currency is
efficient because a single system can be used by all the cells in the body.
Section: 2.12
Learning Outcome: 2.22
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
5) Explain why chemical reactions in the body are often irreversible.
Answer: Chemical reactions that release energy cannot be reversed unless energy is put back
into the system. Also, some reactions produce molecules in excessive quantities (like CO2 and
NH4) that the body then eliminates, but which are needed to reverse a reaction.
Section: 2.5
Learning Outcome: 2.12
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
6) Describe the factors that affect chemical reaction rates.
Answer: Temperature increases kinetic energy and therefore the force of molecular collisions.
Particle size: smaller particles move faster at the same temperature and therefore collide more
frequently; also, smaller particles have more surface area given the same concentration of
reactants. Concentration: the higher the concentration, the greater the chance of particles
colliding. Catalysts increase the rate of the reaction at a given temperature. Enzymes are
biological catalysts.
Section: 2.5
Learning Outcome: 2.13
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
7) Protons and electrons exist in every atom nucleus except hydrogen. Is this statement true or
false and why?
Answer: False. Hydrogen has one proton and one electron. It is the neutron, not the electron that
can coexist in the nucleus and that hydrogen does not have.
Section: 2.2
Learning Outcome: 2.4
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
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Copyright ยฉ 2016 Pearson Education, Ltd.
8) A chemical bond never occurs between components of a mixture. Discuss this.
Answer: Mixtures come in three forms๎solutions, colloids, and suspensions. Components of
these mixtures always retain their original makeup and can be separated into their individual
components; therefore no chemical bonding has taken place.
Section: 2.3
Learning Outcome: 2.6
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
9) All chemical reactions are theoretically reversible. Comment on this statement.
Answer: It is possible to reverse any reaction if the products are still present. Those that are only
slightly exergonic are easily reversible. Some would require an enormous amount of energy to
reverse. In the simple reaction Na + Cl โ NaCl the amount of energy it takes to reverse table salt
to chlorine gas and sodium metal is enormous. When glucose is oxidized the energy goes into
bonds of ATP molecules which are then spent and thus the energy is not available to reform
glucose.
Section: 2.5
Learning Outcome: 2.12
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
10) What is the major difference between polar and nonpolar covalent bonds?
Answer: Polar bonds have an unequal sharing of electrons resulting in a slight negative charge at
one end of the molecule and a slight positive charge at the other end. Nonpolar bonds have an
equal sharing of electrons, resulting in a balanced charge among the atoms.
Section: 2.4
Learning Outcome: 2.10
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
11) An amino acid may act as a proton acceptor or donor. Explain.
Answer: Amino acids have two components๎a base group (proton acceptor) and an organic acid
part (a proton donor). Some have additional base or acid groups on the ends of their R groups as
well.
Section: 2.10
Learning Outcome: 2.19
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
12) Name at least four things you know about enzymes.
Answer:
1. Most are proteins.
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Copyright ยฉ 2016 Pearson Education, Ltd.
2.They have specific binding sites for specific substrates.
3.They lower the activation barrier for a specific reaction.
4.The names often end in “ase.”
5.They can be denatured.
6.They can be used again and again.
Section: 2.10
Learning Outcome: 2.20
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
13) In the compound H2CO3, what do the numbers 2 and 3 represent?
Answer: The 2 indicates that there are two hydrogen atoms in the compound and the 3 indicates
that there are three oxygen atoms in the compound.
Section: 2.5
Learning Outcome: 2.11
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 3 Application
14) Are all chemical reactions reversible? If not, why aren’t they all reversible?
Answer: All chemical reactions are theoretically reversible, but only if the products are not
consumed and enough energy is available for the reaction.
Section: 2.5
Learning Outcome: 2.12
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 2 Comprehension
1.5 Clinical Questions
1) Although his cholesterol levels were not high, Mr. Martinez read that cholesterol was bad for
his health, so he eliminated all foods and food products containing this molecule. He later found
that his cholesterol level dropped only 20%. Why did it not drop more?
Answer: Cholesterol is produced by the liver, in addition to being ingested in foods.
Section: 2.9
Learning Outcome: 2.18
Global LO: G2, G5, G8
HAPS LO: HAPS1, HAPS6, HAPS11
Bloom’s Level: 3 Application
2) How can DNA be used to “fingerprint” a suspect in a crime?
Answer: The DNA of a person is unique to that individual. By obtaining the DNA from
nucleated cells from the crime scene (e.g., blood, semen, other body tissues), enzymes may be
used to break up the DNA into fragments. Because nearly everyone’s DNA is different, it also
breaks up into fragments differently. When the fragments are separated, they form patterns even
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Copyright ยฉ 2016 Pearson Education, Ltd.
more unique than fingerprint patterns. A match of suspect and crime scene DNA is strong
evidence.
Section: 2.11
Learning Outcome: 2.21
Global LO: G2, G5, G8
HAPS LO: HAPS1, HAPS6, HAPS11
Bloom’s Level: 3 Application
3) Why is it possible for us to drink a solution that contains a mixture of equal concentration of a
strong acid and a strong base, either of which, separately, would be very caustic?
Answer: When an acid and base of equal strength are mixed, they undergo a displacement
(neutralization) reaction to form water and a salt.
Section: 2.6
Learning Outcome: 2.15
Global LO: G2, G8
HAPS LO: HAPS1, HAPS11
Bloom’s Level: 3 Application
4) A 65-year-old patient came to the emergency room with complaints of severe heartburn
unrelieved by taking a “large handful” of antacids. Would you expect the pH to be high or low?
Explain why.
Answer: You would expect a high pH. Taking antacids will neutralize the acidic stomach.
Taking a “handful” of antacids can cause an alkaloid state. Certain drugs, such as corticosteroids
and antacids that contain baking soda, will lead to metabolic alkalosis.
Section: 2.6
Learning Outcome: 2.15
Global LO: G2, G5, G8
HAPS LO: HAPS1, HAPS6, HAPS11
Bloom’s Level: 3 Application
5) A 23-year-old male was riding his road bike in 100-degree heat, when he suddenly became
nauseated and weak. He called 911 from his cell phone. When the ambulance came, the
paramedics started intravenous therapy for severe dehydration. Explain the critical role of water
to maintain homeostasis.
Answer: Water is the most abundant and important inorganic compound in living material. It
makes up 60% to 80% of the volume of most living cells. The properties of water are: high heat
capacity, high heat of vaporization, polar solvent properties, reactivity, and cushioning. In this
case the bicyclist lost a large amount of water through perspiration in an effort to cool his body.
This caused a disruption in homeostasis.
Section: 2.6
Learning Outcome: 2.14
Global LO: G2, G8
HAPS LO: HAPS1, HAPS3, HAPS6, HAPS11
Bloom’s Level: 3 Application
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